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Below is a list of all AMaRC trials:
RIDDLE-M-X FOR TRANSPLANT ELIGIBLE NEWLY DIAGNOSED MULTIPLE MYELOMA (PHASE II)

Risk and response adaptive trial evaluating the addition of Selinexor to standard of care therapy for transplant-eligible, newly diagnosed multiple myeloma

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MY-PROMPT-2

More efficient delivery of high-cost standard-of-care therapies in relapsed multiple myeloma using real-time feedback of patient reported outcome measures.

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IBIS FOR FUNCTIONAL HIGH RISK MULTIPLE MYELOMA (PHASE II)

An immuno-therapeutic salvage strategy for 'functional' high-risk (FHR) multiple myeloma incorporating Iberdomide, Isatuximab and Dexamethasone.

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FRAIL-M FOR TRANSPLANT INELIGIBLE MYELOMA (PHASE I/II)

Frailty-stratified, randomised controlled Bayesian adaptive trial of bortezomib versus lenalidomide in transplant-ineligible myeloma (TI-NDMM) – the FRAIL-M study

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PRO FOR PATIENTS RECEIVING DVD **recruitment closed**

Patient Reported Outcomes in patients receiving DVd for relapsed multiple myeloma.

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BelaCarD FOR RELAPSED REFRACTORY MULTIPLE MYELOMA (PHASE I/II) **recruitment closed**

A phase I/II single arm study of combination belantamab mafodotin, carfilzomib and dexamethasone in patients with early relapsed multiple myeloma.

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IRIL FOR TRANSPLANT INELIGIBLE MYELOMA (PHASE II) **recruitment closed**

A prospective Phase II study of Isatuximab Rescue for Inadequate response to Lenalidomide and Dexamethasone in transplant ineligible patients with newly diagnosed multiple myeloma (IRIL)

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VCD-D FOR TRANSPLANT INELIGIBLE MYELOMA (Phase II) **recruitment closed**

A randomized phase 2 study of bortezomib, cyclophosphamide and dexamethasone induction (VCD) compared with VCD and daratumumab induction followed by daratumumab maintenance (VCDD) for the initial treatment of transplant ineligible patients with multiple myeloma

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V-VCD FOR TRANSPLANT ELIGIBLE MYELOMA (PHASE II) **recruitment closed**

An exploratory study of Venetoclax in combination with Bortezomib-Cyclophosphamide-Dexamethasone (VCD) induction therapy in newly diagnosed transplant eligible (NDTE MM) multiple myeloma with proteomic correlative studies

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KappaMab FOR RELAPSED REFRACTORY MULTIPLE MYELOMA (Phase IIb) **recruitment closed**

A Phase IIb, open label, sequential cohort study comparing KappaMab alone to KappaMab in combination with lenalidomide and low dose dexamethasone (MRd) in Relapsed Refractory Multiple Myeloma

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ITD FOR RELAPSED REFRACTORY MULTIPLE MYELOMA (PHASE II) **recruitment closed**

A prospective, multi-centre, single arm, phase 2 assessment of the efficacy and safety of the combination of ixazomib, thalidomide and dexamethasone (ITD) for relapsed and/or refractory multiple myeloma after 1 to 3 prior lines of therapy.

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For further information about our clinical trials, please contact us.